The NTRK3 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to NTRK3, and TrkC. This antibody recognizes Human antigen. The NTRK3 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Background: NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers